Pulse blood pressure and cardiovascular mortality in a population-based cohort of elderly Costa Ricans

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dc.contributor.author Rosero-Bixby, Luis
dc.contributor.author Coto Iglesias, Fernando
dc.contributor.author Dow, William H.
dc.date.accessioned 2016-07-06T17:45:34Z
dc.date.available 2016-07-06T17:45:34Z
dc.date.issued 2015
dc.identifier.issn 0950-9240
dc.identifier.uri http://biblioteca.ccp.ucr.ac.cr/handle/123456789/967
dc.description.abstract We studied the relationships between blood pressure (BP), pulse pressure (PP) and cardiovascular (CV) death in older adults using data from 2346 participants enrolled in the Costa Rican CRELES study, mean age 76 years (s.d. 10.2), 31% qualified as wide PP. All covariates included and analyzed were collected prospectively as part of a 4-year home-based follow-up; mortality was tracked for an additional 3 years, identifying 266 CV deaths. Longitudinal data revealed little change over time in systolic BP (SBP), a decline in diastolic BP, and widening of PP. Wide PP was associated with higher risk of CV death but only among individuals receiving antihypertensive drug therapy. Individuals with both wide PP and receiving therapy had 2.6 hazard rate of CV death relative to people with normal-PP plus not taking treatment (TRT), even adjusting for SBP. Increasing PP between visits was significantly associated to higher CV death independently of TRT status. SBP and DBP were not significantly associated to CV death when the effect of PP was controlled for. Conclusion: elderly hypertensive patients with wide or increasing PP, especially if receiving TRT, are the highest CV risk group, thus must be carefully assessed, monitored and treated with caution. es
dc.language.iso en en
dc.publisher Macmillan Publishers Limited es
dc.rights Atribución-NoComercial-CompartirIgual 3.0 Costa Rica *
dc.rights.uri http://creativecommons.org/licenses/by-nc-sa/3.0/cr/ *
dc.subject Mortalidad es
dc.subject Adulto mayor es
dc.subject Enfermedades cardiovasculares es
dc.title Pulse blood pressure and cardiovascular mortality in a population-based cohort of elderly Costa Ricans es
dc.title.alternative Journal of Human Hypertension es
dc.type Article es

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Atribución-NoComercial-CompartirIgual 3.0 Costa Rica Except where otherwise noted, this item's license is described as Atribución-NoComercial-CompartirIgual 3.0 Costa Rica

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