Genetic polymorphism of CYP1A2 increases the risk of myocardial infarction

dc.contributor.author	Cornelis, Marilyn C.
dc.contributor.author	El-Sohemy, Ahmed
dc.contributor.author	Campos, Hannia
dc.date.accessioned	2016-07-11T16:47:24Z
dc.date.available	2016-07-11T16:47:24Z
dc.date.issued	2004
dc.identifier.issn	1468-6244
dc.identifier.uri	http://biblioteca.ccp.ucr.ac.cr/handle/123456789/1065
dc.description.abstract	There is growing evidence that DNA damage caused by mutagens found in tobacco smoke may contribute to the development of coronary heart disease (CHD). In order to bind to DNA many mutagens require metabolic activation by cytochrome P450 (CYP) 1A1 or CYP1A2. The objective of this study was to determine the effects of CYP1A1 and CYP1A2 genotypes on risk of myocardial infarction (MI) and whether smoking interacts with genotype to modify risk.	en
dc.language.iso	en	en
dc.publisher	BMJ	en
dc.rights	Atribución-NoComercial-CompartirIgual 3.0 Costa Rica	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-sa/3.0/cr/	*
dc.subject	Enfermedades cardiovasculares	es
dc.subject	Tabaquismo	es
dc.title	Genetic polymorphism of CYP1A2 increases the risk of myocardial infarction	en
dc.title.alternative	Journal of Medical Genetics. 41 (10)	en
dc.type	Article	en